Nutritional and hormonal regulation of genes for lipogenic enzymes
نویسندگان
چکیده
منابع مشابه
Nutritional and hormonal regulation of genes for lipogenic enzymes.
The de novo synthesis of long-chain fatty acids, a process that occurs primarily in liver in many species, is high in animals fed on diets with a high content of carbohydrate, and low in starved animals. The activities of the ‘lipogenic’ set of hepatic enzymes follow the same pattern. Two members of this lipogenic set are cytosolic malic enzyme (EC 1.1.1.40), which furnishes most of the NADPH f...
متن کاملNutritional regulation of the activities of lipogenic enzymes of rat liver and brown adipose tissue.
Nutrition-induced effects on the activity of enzymes of lipogenesis, fatty acid synthase (FAS: EC 2.3.1.85), ATP citrate lyase (ACL: EC 4.1.3.8), malic enzyme (ME; EC 1.1.1.40), glucose-6-phosphate dehydrogenase (G6PDH: EC 1.1.1.49) and 6-phosphogluconate dehydrogenase (PGDH; EC 1.1.1.44) were investigated in liver and interscapular brown adipose tissue (BAT) of rats. The lipogenic enzymes coul...
متن کاملExpression and nutritional regulation of lipogenic genes in the ruminant lactating mammary gland.
The effect of nutrition on milk fat yield and composition has largely been investigated in cows and goats, with some differences for fatty acid (FA) composition responses and marked species differences in milk fat yield response. Recently, the characterization of lipogenic genes in ruminant species allowed in vivo studies focused on the effect of nutrition on mammary expression of these genes, ...
متن کاملMechanisms of nutritional and hormonal regulation of lipogenesis.
Fat build-up is determined by the balance between lipogenesis and lipolysis/fatty acid oxidation. In the past few years, our understanding of the nutritional, hormonal and particularly transcriptional regulation of lipogenesis has expanded greatly. Lipogenesis is stimulated by a high carbohydrate diet, whereas it is inhibited by polyunsaturated fatty acids and by fasting. These effects are part...
متن کاملPhysiological and nutritional regulation of enzymes of triacylglycerol synthesis.
Although triacylglycerol stores play the critical role in an organism's ability to withstand fuel deprivation and are strongly associated with such disorders as diabetes, obesity, and atherosclerotic heart disease, information concerning the enzymes of triacylglycerol synthesis, their regulation by hormones, nutrients, and physiological conditions, their mechanisms of action, and the roles of s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1991
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19910022